Lidwien Jansen
28/7/2026
2
 min leestijd
Minerals

Brain fog symptoms: could mineral deficiencies play a role?

Do your thoughts keep slipping away and does your head feel constantly foggy? You might be missing more than just focus

Brain fog. A term that is popping up more and more. Being unable to focus. Thoughts slipping away. Reading a paragraph three times. Forgetting what you were just about to say. Fatigue that is present in the morning, even before you have done anything. Shortness of breath when climbing stairs. Stamina that is slowly but surely getting worse. Headaches that are just part of the deal. Restless legs in the evening. Dizziness when standing up quickly.

Brain fog symptoms can significantly disrupt your daily life. Could these brain fog symptoms be caused by a mineral deficiency? It is possible, but the connection is more complex than is often suggested.
A deficiency can affect the functioning of the body and the brain.

What are brain fog symptoms?

Brain fog is not an official medical diagnosis. It is a collective term for complaints related to thinking, attention, memory, and mental energy. Brain fog does not have a single cause, but according to experts, you can take certain steps to combat the symptoms by looking at your lifestyle.

Common brain fog symptoms include:

  • difficulty concentrating;
  • becoming easily distracted or overstimulated;
  • thoughts suddenly slipping away;
  • forgetting what you wanted to say or do;
  • difficulty finding the right words;
  • trouble remembering recent information;
  • slower thinking and reacting;
  • processing information less quickly;
  • having to read texts multiple times;
  • difficulty following conversations;
  • trouble with planning and organizing;
  • difficulty making decisions;
  • inability to multitask effectively;
  • finding simple tasks overwhelming;
  • making more mistakes than usual;
  • mental fatigue after exertion;
  • a dull, foggy, or spaced-out feeling.

Not everyone experiences the same symptoms. For some, forgetfulness is the primary issue, while others struggle more with mental slowness or difficulty reading and speaking. The severity can also fluctuate from day to day or even hour to hour. If

What does brain fog feel like?

Brain fog is often described as thinking through a thick haze. You are awake, but you don't feel sharp. Information comes in, but it doesn't seem to be processed or stored correctly. You walk into a room and forget why you went there. You lose your train of thought during a conversation. You open an email and forget what it said after the first few lines. A task that used to be second nature suddenly requires a step-by-step approach. This can cause feelings of insecurity.

People sometimes worry that their memory is severely declining, when the problem may actually stem from temporary disruptions in attention, information processing, and mental energy.

Physical symptoms alongside brain fog

Brain fog symptoms can occur alongside other physical complaints, such as:

  • persistent fatigue;
  • headaches;
  • dizziness when standing up;
  • poor or unrefreshing sleep;
  • shortness of breath during exertion;
  • heart palpitations;
  • restless legs;
  • reduced stamina;
  • irritability;
  • feeling down or anxious;
  • sensitivity to light and sound.

Hair loss, brittle nails, and pale skin are not direct symptoms of brain fog. However, when these occur alongside fatigue and concentration problems, they may point to an underlying issue, such as an iron deficiency.

Can mineral deficiencies cause brain fog?

Minerals are essential for nerve cell function, energy production, oxygen supply, and the immune system. Our bodies cannot produce these substances themselves; we must obtain them daily through food and drinking water.

And that is exactly where the problem lies. Our modern diet does not always provide sufficient minerals. Many people have unbalanced diets, consume many highly processed products, and do not get enough mineral-rich foods.
In addition, soil conditions, cultivation, processing, and preparation can affect mineral content.
Blood loss, increased demand, or poor absorption in the gut can also cause a deficiency.

A proven deficiency can contribute to fatigue, weakness, and cognitive complaints.
The link is usually indirect:
insufficient intake, increased loss, or poor absorption → mineral deficiency → impaired bodily functions → fatigue and cognitive complaints

However, brain fog alone does not prove that someone has a deficiency. These symptoms can also occur with sleep deprivation, stress, hormonal changes, medication use, and various physical conditions.

Iron deficiency and brain fog symptoms

Of all minerals, iron has the clearest link to a combination of fatigue and concentration problems. The body needs iron to produce hemoglobin, a protein in red blood cells that transports oxygen to tissues. Prolonged iron deficiency can lead to anemia, which makes it harder for the body to transport oxygen efficiently.

Possible symptoms of iron deficiency or anemia include:

  • severe fatigue;
  • concentration problems;
  • headaches;
  • dizziness;
  • pale skin;
  • heart palpitations;
  • shortness of breath during exertion;
  • restless legs;
  • brittle nails;
  • hair loss.

Low iron stores without clear anemia can also sometimes be associated with symptoms. The relationship is less straightforward in such cases. Whether a deficiency truly exists can only be determined through blood tests.

Read more here about iron deficiency

Magnesium and brain fog

Magnesium is essential for hundreds of processes in the body. It helps convert nutrients into energy, supports nerve impulse transmission, and is involved in the functioning of muscles, the brain, and the immune system. Magnesium also plays a role in regulating inflammatory responses and protecting cells against oxidative stress.
A deficiency can manifest as fatigue, muscle weakness, cramps, irritability, and concentration problems.
The risk of a deficiency increases with a restrictive diet, chronic intestinal issues, frequent alcohol consumption, and the use of certain medications, including some antacids and diuretics. Persistent diarrhea and poorly managed diabetes can also lead to additional magnesium loss.

However, like other minerals, magnesium does not function in isolation. It works closely with calcium, potassium, sodium, and phosphate, among others. Vitamin D is also important for maintaining this balance. Consequently, a disruption in one mineral can affect the absorption, excretion, or function of others.
That is why simply taking magnesium supplements is not always the best approach.
A single supplement does not resolve a restrictive diet, poor absorption, or a broader disruption of the mineral balance. The foundation remains, of course, a varied diet including green leafy vegetables, nuts, seeds, legumes, and whole-grain products.

Iodine and the thyroid

Iodine is necessary for the production of thyroid hormones. These hormones influence metabolism, energy, and brain function, among other things.

A long-term iodine deficiency can contribute to an underactive thyroid. Potential symptoms include:

  • fatigue;
  • sluggish thinking;
  • memory and concentration problems;
  • feeling cold;
  • weight gain;
  • dry skin;
  • constipation.

An underactive thyroid can have various causes. I know from personal experience how much of an impact it can have. Years ago, I was diagnosed with an underactive thyroid myself. The expectation was that I would have to take medication for the rest of my life. I didn't just accept that prospect.
I decided to thoroughly adjust my diet and started using SMPL72. I haven't had any thyroid issues since. That was years ago now.
My experience is not scientific proof that SMPL72 treats a thyroid condition or can replace medication. I want to be clear about that. However, it is my personal experience, and that is why I feel it is worth sharing.

Zinc, selenium, and copper

Zinc, selenium, and copper are trace elements: the body only needs small amounts of them. They support enzymes, nerve cells, and the immune system.

A severe deficiency can affect the immune system and the nervous system. However, these deficiencies are not a common explanation for everyday brain fog. Furthermore, more is not automatically better.

Too much zinc, for example, can block the absorption of copper. This can lead to a copper deficiency, potentially causing anemia and neurological symptoms. An excess of selenium can actually cause hair loss, brittle nails, and nerve problems. Symptoms that resemble a deficiency can therefore sometimes be caused by an excess.

Minerals and neuroinflammation

Scientists are investigating whether deficiencies in certain minerals can contribute to neuroinflammation. This is an immune response in the brain and the rest of the nervous system.

In the brain, such a response is partly controlled by microglia. These are specialized immune cells that react to infections, damage, and other threats. Temporary activation helps protect and repair the brain. When microglia remain active for too long or too intensely, inflammatory substances may disrupt communication between nerve cells.

A possible process is:

mineral deficiency → increased oxidative stress → immune cell dysregulation → microglia activation → disruption of neuronal communication

Magnesium and zinc, in particular, are being studied in this context. Animal and laboratory research suggests that a magnesium deficiency can activate inflammatory pathways and microglia. An impaired zinc balance can also affect the regulation of inflammatory responses.

While this provides a biologically plausible explanation, it is not yet hard evidence that mineral deficiencies are a common cause of brain fog in humans via neuroinflammation. Many findings come from cell and animal studies and cannot be directly translated to patients with brain fog.

A deficiency can also cause symptoms without neuroinflammation

A mineral deficiency does not need to cause brain inflammation to result in cognitive symptoms.

In the case of an iron deficiency, for example, anemia can affect oxygen supply. With an iodine deficiency, cognitive symptoms can arise due to insufficient thyroid hormones. A severe magnesium deficiency can disrupt the normal functioning of nerve and muscle cells.

It is therefore too simplistic to categorize all brain fog caused by deficiencies under the umbrella of neuroinflammation. Sometimes there is a more direct explanation. In other cases, it is not yet clear which mechanism is responsible.

Why are minerals poorly absorbed?

A deficiency does not always occur because someone is not eating enough of a mineral. Sometimes the body is unable to absorb nutrients properly.

Reduced absorption can occur with, among other things:

  • celiac disease;
  • Crohn's disease;
  • other chronic intestinal disorders;
  • prolonged diarrhea;
  • gastric or intestinal surgery;
  • long-term use of certain antacids.

Other factors also play a role. For example, blood loss due to heavy menstruation or gastrointestinal bleeding can cause an iron deficiency.

Foods can also influence each other's absorption. Coffee and tea reduce iron absorption when consumed around an iron-rich meal. Vitamin C, on the other hand, promotes the absorption of plant-based iron.

Other possible causes of brain fog symptoms

Mineral deficiencies are just one possible explanation. Brain fog can also be associated with:

  • insufficient or disrupted sleep;
  • prolonged stress and overload;
  • post-COVID;
  • ME/CFS;
  • hormonal changes or menopause;
  • depression and anxiety;
  • chronic pain;
  • certain medications;
  • an underactive thyroid;
  • migraines;
  • recovery after an infection or surgery;
  • chemotherapy;
  • a vitamin B12 or folate deficiency.

Vitamin B12 and folate are not minerals, but deficiencies can cause anemia, fatigue, and neurological or cognitive issues.

There is often not just one single cause. Poor sleep, pain, stress, and physical fatigue can reinforce one another, making it increasingly difficult to concentrate and remember things.

Why random supplementation is not a good idea

When dealing with brain fog, people often reach for a single magnesium, iron, or zinc supplement. But taking a high dose of just one mineral is a shot in the dark. Minerals work together and influence each other's absorption and function. Too much zinc, for example, can cause a copper deficiency, while an excess of iron, iodine, or selenium can also be harmful.

SMPL72 does not consist of one isolated mineral, but is a 100% natural mineral source in which various minerals occur together. Linked to fulvic acid, the transport agent that ensures the minerals reach the cell.
Straight from nature. This supports the mineral balance through a broad composition, rather than with one randomly high-dosed mineral.

What uou take Isn’t necessarily what your cells receive

Between mineral intake and their actual use by your cells lies a complex biological pathway. A mineral listed on a label is not yet a mineral inside a cell. First, it must be released from its food matrix or compound during digestion. Stomach acidity, digestive enzymes, and the mineral’s chemical form then determine how well it remains soluble. Only in a suitable, soluble form can the mineral reach the intestinal wall and be absorbed through specific transport proteins or ion channels.

This absorption is tightly regulated. Intestinal cells do not allow minerals to pass through without restriction; they respond to the body’s needs, existing mineral stores, and the presence of other substances. Minerals can work together, but they can also compete with one another. High doses of zinc, for example, can disrupt copper balance. Calcium, magnesium, iron, and other minerals may also use overlapping absorption pathways or influence one another’s availability. A large amount of a single isolated mineral therefore does not guarantee better absorption and may actually disturb the overall balance.

Once minerals have crossed the intestinal wall, the next phase begins. They are transported through the bloodstream, often bound to carrier proteins, and must then reach the correct tissue. From there, they need to enter the cell, arrive in the right cellular compartment, and become available to enzymes and other cellular processes. Magnesium, for example, is required for reactions involving ATP: the cell’s energy carrier functions primarily as a magnesium–ATP complex. Iron is essential not only for haemoglobin but also for mitochondrial enzymes involved in energy production. Zinc supports hundreds of enzymes and regulatory processes, while selenium forms part of enzymes that help protect cells against oxidative damage.

Balance remains essential inside the cell as well. Minerals do not function as isolated components but as cofactors within complex networks of enzymes, electrical gradients, and signalling pathways. Cells must continuously maintain the correct concentrations. Too little can slow down essential processes, while too much can be equally disruptive or even toxic. The body therefore uses transporters, storage proteins, and excretory mechanisms to regulate mineral balance precisely.

This is the thinking behind SMPL72: instead of simply stacking more and more isolated substances, the focus is on the form, relationship, and availability in which minerals are provided. SMPL72 contains fulvic acid that is naturally associated with a broad spectrum of minerals and trace elements. Due to its chemical properties, fulvic acid can interact with mineral ions and influence their solubility. How much is ultimately absorbed and used by cells still depends on factors including dosage, intestinal function, individual requirements, and the overall diet.

The principle is simple, yet biologically fundamental: mineral intake does not automatically equal mineral absorption, and absorption does not automatically mean that your cells can use those minerals. Minerals only realise their true value when they are soluble, cross the intestinal barrier, reach the correct tissue, and become available for the processes in which the body needs them. Learn more about the SMPL72 philosophy.

Read the blog: Mineral complex, not every supplement is as natural as it seems

Read: what fulvic acid is, how it works, what it does, and why you need it.

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