Industry
PFAS: the ‘forever’ toxin that quietly undermines your health
PFAS may seem harmless, but it is now classified as a Substance of Very High Concern. It is in your blood and does not break down. What can you do about it?
PFAS may seem harmless, but it is now classified as a Substance of Very High Concern. It is in your blood and does not break down. What can you do about it?
You have it. Your children do, too. Even if you live on organic food, spring water, and healthy habits, there is a good chance that PFAS is in your blood. According to the RIVM, this applies to almost everyone in the Netherlands. Not because we ingest it intentionally, but because it is everywhere. In pizza boxes, raincoats, mascara, dental floss, drinking water, and dust. The industry runs on it. It is even in the air you breathe. PFAS is like an invisible roommate who never announces their presence—but leaves traces everywhere.
Yet, PFAS is not a "classic poison." It doesn't bite. It doesn't burn. It doesn't bind to anything. It is chemically so stable that it barely reacts with anything or anyone. In chemistry, this is called "inert." And "inert" sounds reassuring. After all, if something does nothing, it can't do any harm, right? So what are we worried about? How can a substance that doesn't bind to anything still undermine your health?
How a substance that doesn't bind to anything can still undermine your health
At first glance, it sounds reassuring: PFAS is inert. A molecule that barely reacts, does not bind to fats or cell structures, and doesn't really seem to get in anywhere. So how dangerous can it be? After all, "inert" means stable, sluggish, and chemically indifferent. Not like a poison that nests in your organs. Not like a substance that destroys everything. And yet, the RIVM calls PFAS "concerning," blood concentrations are closely monitored, and the number of studies linking it to suppressed immunity, high cholesterol, fatty liver disease, developmental disorders, and certain cancers is growing.
A circulating nuisance
PFAS are inventions of the twentieth century. In the 1940s, chemical giant DuPont developed Teflon. Other manufacturers followed with applications in raincoats, firefighting foam, pizza boxes, makeup, and non-stick pans. The molecular strength of PFAS lies in its structure: the carbon-fluorine bond is one of the strongest in chemistry. Good news for industrial applications. Bad news for all living things.
PFAS are persistent. This means they do not break down. Not in the environment. Not in the body. Not over time. This has earned them the nickname "forever chemicals"—and rightly so. While other toxins accumulate in fatty tissue or are eliminated through waste, PFAS continue to circulate in your blood for years. They do this without classically binding to fats or cell structures. Instead, they attach themselves to proteins in the blood, such as albumin. Through this route, they reach the liver, kidneys, thyroid, and other organs sensitive to biochemical disruption.
PFAS—per- and polyfluoroalkyl substances—are not classic toxins. They do not accumulate in fat like PCBs, and they do not hide in bone tissue like lead. What they do is persist in your blood for years. Not because they bind to you, but because you cannot get rid of them.
PFAS is both hydrophobic and lipophobic. This means it mixes with neither fat nor water. Your body, which runs largely on fat and water, literally has no grip on this substance. It slips through everything. There is no natural drainage route. No breakdown. No storage. Only circulation. Slowly. Year in, year out.
Some variants of PFAS have a half-life of more than eight years. And that is for a single exposure. In reality, we are exposed daily—through tap water, cosmetics, food packaging, clothing, and household dust. Even organic vegetables can contain PFAS via irrigation water or contaminated soil.
Not a poison, but a saboteur
But still: what makes something that is inert a risk? The answer is: subtle, chronic disruption. Don't think of a hammer smashing something. Think of a fake key that slowly wears down the lock. PFAS mimics the body's own substances—such as fatty acids—and thereby hijacks sites in your system that are crucial for regulation.
Scientists have shown that PFAS binds to blood plasma proteins such as albumin (Peng et al., 2024). Through this route, it reaches the liver, kidneys, and thyroid. It does not bind permanently there, but it does influence biological processes. For example, by activating receptors such as PPARα and PPARγ, which play a key role in fat metabolism, inflammatory responses, and hormonal balance (in vitro studies, BioMed Central & ResearchGate).
In other words: PFAS does not need to enter the cell. It does not need to be stored. It does not even need to bind in massive quantities. It only needs to be present in the wrong places—and for long enough—to slowly throw your body's regulation out of balance.
You only notice it years later
That makes PFAS not an acute threat. You don't get sick from it like you do from salmonella. You don't notice it like an allergy. PFAS is the type of disruption you only see in trends, in population studies, and in statistics. It increases the risk of autoimmune diseases. It reduces the effectiveness of vaccinations. It disrupts cholesterol regulation. It increases the risk of liver problems.
In 2022, an international working group concluded that no safe level of exposure to PFAS can be established. Not because it is acutely lethal—but because long-term exposure at low concentrations already leads to significant health problems.
And then what? What can your body do with it?
Actually, nothing. That is the painful answer. Because PFAS does not bind to fat or cell structures, your body cannot easily eliminate it. It doesn't recognize it as dangerous, so it sees no reason to transport it out via the bile, kidneys, or intestines.
This makes PFAS a unique enemy. It is not an intruder that hides—it is not an intruder that breaks things. It is a silent guest who sits on your couch, speaks your language, and quietly turns the dials on your thermostat.
SMPL72 Fulvic Acid: a helper on the sidelines
In the search for ways to help clear PFAS from the body, people often look at binders, saunas, fibers, and supportive substances. One of these is fulvic acid.
SMPL72 Fulvic Acid is exceptionally small, has a negative charge, and possesses many free binding sites. Laboratory studies have shown that it can bind to pesticides, heavy metals like lead and cadmium, and antibiotic residues. Furthermore, it supports the absorption of minerals such as zinc and selenium and enhances the function of glutathione—the most powerful antioxidant your body produces itself.
However, SMPL72 fulvic acid is not a proven solution for PFAS. To date, there are no animal or human studies demonstrating that it removes PFAS from the blood. There are, however, indications that it might bind residual fractions in the gut or support the body in a broader sense with systemic detox.
That is also how some integrative physicians use it: not as a wrecking ball, but as a helper. In combination with good nutrition and sweat activation (sauna, exercise), SMPL72 fulvic acid could contribute to easing the burden.
What does the science say so far?
Albumin binding: PFAS binds to serum albumin, a transport protein in the blood (Peng et al., 2024), and thus reaches the liver, kidneys, and thyroid.
Receptor interference: PFAS activates nuclear receptors such as PPARs, which are involved in fat metabolism, inflammation, and hormone regulation (ResearchGate, 2022).
Chronic disruption: Long-term exposure leads to increased cholesterol, reduced immunity, and a higher risk of certain cancers (Environmental Health, 2023).
Inert ≠ harmless
And that is perhaps the most important lesson. The fact that something doesn't bind doesn't mean it does nothing. Sometimes it is precisely the absence of binding, the absence of recognition, that makes a substance so dangerous. PFAS is not toxic because it breaks something, but because it pulls your body just enough out of balance for decades to cause damage unnoticed.
You don't see it. You don't feel it. But it is there. And it stays.
What SMPL72 does do
We’ll tell it like it is: SMPL72 does not remove PFAS from your blood. That has not (yet) been proven. What is proven: fulvic acid binds to heavy metals and pesticides, supports liver function, promotes cell repair, and improves the absorption of essential minerals like zinc and selenium. That doesn't make it a miracle cure, but it does make it a valuable helper in the great work your body does every day.
Not proven against PFAS. But logical as part of a broader detox strategy, in which nutrition, elimination, and support are central. Supported by studies published in MDPI and Frontiers in Microbiology.
Everything you want to know about SMPL72, enrollment, and how it works. Still have questions? We've got the answers.
This varies from person to person and depends primarily on your starting point. Fulvic acid supports the absorption and bioavailability of the minerals you already get through your diet or supplements. The faster your body responds to that improved availability, the sooner you will notice a difference. People with low mineral levels or higher requirements often experience changes sooner than those who are already well-nourished. Some users notice more clarity or a calmer energy level within a few days, while for others, it happens more gradually over a period of weeks. In SMPL72, the fulvic acid is naturally bound to 72 different minerals and trace elements. The most important thing is consistency: fulvic acid doesn't act as a quick stimulant, but as a daily absorption mechanism that builds its effect step by step.
People often get some minerals from various sources, but usually not enough. Furthermore, they are often poorly absorbed by the digestive system. It is important to realize that most supplements are synthetic, and in the case of minerals, they are essentially just rock. These contain large molecules that your body can barely absorb, if at all. We have previously written a blog post about the ins and outs of supplementation; feel free to check out our blog section. You might already be taking magnesium or zinc, but keep in mind that you are only taking one or two of the 60 minerals your body needs every day. When you think in terms of a complementary approach, you cannot simply pick one mineral out of the entire spectrum.
Fulvic acid is not an energy booster, nor is it a substance that provides an immediate effect on fatigue or concentration. What it does is something more fundamental: it supports the way your body absorbs and utilizes minerals. And that very point—the utilization of minerals—plays a bigger role for many people than they realize. Fatigue, "brain fog," and concentration issues often have multiple causes, but in orthomolecular practice, it is frequently observed that mineral metabolism and electrolyte balance are significant factors. Minerals are necessary for processes such as: - signal transmission in the nervous system - energy production in the mitochondria - oxygen transport - fluid balance in and around the cell - enzyme activity involved in focus, alertness, and metabolism If those minerals are insufficiently available at the cellular level, the body cannot perform these processes efficiently. Fulvic acid cannot solve that on its own, but it makes minerals chemically smaller, more soluble, and more accessible to the body. As a result, the minerals you ingest through food or supplements can be better utilized where they are needed. Many users experience a more stable energy level, greater clarity, or fewer fluctuations throughout the day. Not because fulvic acid provides a direct stimulant, but because minerals are able to do their job better. This is a fundamentally different mechanism than that of caffeine, stimulants, or "energy boosters." It remains important to emphasize: fulvic acid is not a treatment for fatigue or concentration issues. It merely supports the biological foundation upon which energy, clarity, and nerve function operate. What an individual notices from it naturally also depends on diet, hydration, lifestyle, and individual needs.
Fulvic acid has a very mild, almost neutral taste. Most people barely notice it when they add a few drops to a glass of water. Some describe it as having a very light mineral flavor, but you usually only notice it if you are really paying attention. SMPL72 is pure fulvic acid with no additives, which keeps the taste soft, clean, and subtle. You don't need to worry about a bitter, sharp, or "muddy" taste, which is common in impure or thick humic products.Most users find that it simply tastes like water with a very faint hint of minerality. This makes it easy to use every day, even for children or people who are sensitive to strong flavors. It is best to take SMPL fulvic acid in a glass of chlorine-free water. Fruit juice is also an option, but avoid hot drinks. It is very easy to use.
Add 7-10 drops daily to a glass of (chlorine-free) water (fruit juice is also an option, but avoid hot drinks). For children: 1 drop per 10 kg of body weight. Feel free to increase the dose during illness or intense physical exertion. For maximum absorption: take 30 minutes before a meal. For an energetic start to the day: take in the morning on an empty stomach. For recovery: take immediately after sports or physical exertion. SMPL72 is a powerful detox, so be sure to drink plenty of water. If you are pregnant or taking medication, build up the dose gradually and monitor how your body reacts. When in doubt, consult your doctor or midwife.
